The decision tree
- Country profile in tightened-review tier (Pakistan, Nigeria, Vietnam, Indonesia, Bangladesh)? → Wise Business primary. Mercury/Relay/Brex as stretch attempts.
- Country profile in mid-tier (India, UAE, Brazil, Philippines)? → Mercury primary. Relay or Wise as backup.
- Country profile in high-tier (UK, EU, Singapore, Japan)? → Mercury primary (~85-95% approval). Brex or Relay as needed.
- Revenue under $50K annual? → Mercury or Wise.
- Revenue $50K-$100K annual? → Mercury primary. Add Relay if you want sub-accounts.
- Revenue $100K+ annual? → Brex becomes feasible. Many keep Mercury and add Brex for credit lines.
- VC-funded ($1M+ raised)? → Brex is the right primary. They love funded startups.
- Running multiple LLCs? → Relay sub-accounts shine. Up to 20 sub-accounts under one LLC structure.
Mercury: when it wins
- Broadest non-resident approval rate (~70% across most country profiles)
- Treasury yield on idle balances (~5% APY via T-bill sweep)
- Native Stripe integration
- API for automation
- Mercury IO Cards (debit + 1.5% cashback)
- FDIC partner coverage up to $5M
Brex: when it wins
- You need high-limit business credit cards ($50K-$500K limits)
- You have $100K+ annual revenue or VC funding
- You spend heavily on ads (Meta, TikTok, Google) and need credit lines
- You want premium expense management (Brex's UX is best-in-class for this)
Relay: when it wins
- You run Profit First budgeting (separate buckets for tax, payroll, owner draw, etc.)
- You operate multiple LLCs and want consolidated banking
- You want sub-accounts per client (for agency businesses)
- Mercury rejected you and you want a chartered US bank alternative
- You value FDIC coverage over speed
When you should open multiple
Common multi-bank setups: Mercury primary + Wise for international clients. Mercury primary + Brex for credit lines. Relay primary (multi-account) + Wise for cross-border payments. Single-bank setups work fine at smaller scale but most founders past $100K revenue open at least two for redundancy and feature stacking.